Shinagawa area is a very convenient area to live in if one often commutes via Shinkansen or planes. The area the outside of the Yamanote line has developed in the last 20 years into a populous skyscraper area with both corporate and residential building. Inside the Yamanote, there are numerous large International hotels including the Prince and Marriott, and many fun amusement actives. Hidden behind the hotel and corporate buildings are lovely hilly streets with many old single family houses.
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